type1error.2TOST

Was designed to calculate the type I error rate of two simultaneous TOST procedures 
(where the two parameters of the two TOSTs are correlated with some correlation)
for various study designs used in BE studies.
Is defunct now since it suffers from insufficient precision to obtain the 
type 1 error (TIE) via simulations. 
Due to the intersection-union principle the TIE is always upper bounded 
to alpha by theory.

Contains functions to calculate power and sample size for
various study designs used in bioequivalence studies. Use known.designs() to
see the designs supported. Power and sample size can be obtained based on
different methods, amongst them prominently the TOST procedure (two one-sided
t-tests). See README and NEWS for further information.

D. Labes

PowerTOST

Power and Sample Size for (Bio)Equivalence Studies

Detlew Labes

Helmut Schütz

Benjamin Lang

type1error.2TOST function

Was designed to calculate the type I error rate of two simultaneous TOST procedures 
(where the two parameters of the two TOSTs are correlated with some correlation)
for various study designs used in BE studies.
Is defunct now since it suffers from insufficient precision to obtain the 
type 1 error (TIE) via simulations. 
Due to the intersection-union principle the TIE is always upper bounded 
to alpha by theory.

type1error.2TOST: Type I error rate for two simultaneous TOST procedures

Description

Arguments