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PowerTOST (version 1.5-6)

ct5.1+ct5.2+ct5.3+ct5.4.1: Sample Size Tables for the Classical 2x2 Crossover Design

Description

These data.frames give sample size tables calculated with sampleN.TOST() for the 2×2 design.

Arguments

Author

PowerTOST

Details

The data.frames can be accessed by their names.

data.frameDescription
ct5.1Multiplicative model, theta1=0.8, theta2=1.25 (1/theta1), exact
ct5.2Multiplicative model, theta1=0.75, theta2=1.3333 (1/theta1), exact
ct5.3Multiplicative model, theta1=0.9, theta2=1.1111 (1/theta1), exact
ct5.4.1Additive model, theta1=--0.2, theta2=+0.2 (BE limits 0.80 -- 1.20), exact

References

Hauschke D, Steinijans VW, Pigeot I. Bioequivalence Studies in Drug Development. Chichester: John Wiley; 2007.

Chow SC, Liu JP. Design and Analysis of Bioavailability and Bioequivalence Studies. Boca Raton: CRC Press; 3rd edition 2009.

Examples

Run this code
ct5.1
ct5.2
ct5.3
ct5.4.1

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