RIbench enables the automated evaluation and comparison of any existing and novel indirect method in a systematic way.
Indirect methods take routine measurements of diagnostic tests, containing pathological and non-pathological samples
as input and use sophisticated statistical methods to derive a model describing the distribution of the non-pathological
samples, which can then be used to derive reference intervals. The benchmark suite contains 5,760 simulated data sets
with varying difficulty.
To include any indirect method, a custom wrapper function needs to be provided.
The package offers functions for generating the test sets generateBiomarkerTestSets,
executing the indirect method evaluateBiomarkerTestSets and evaluating the results evaluateAlgorithmResults.
Tatjana Ammer tatjana.ammer@roche.com, Christopher M Rank christopher.rank@roche.com, Andre Schuetzenmeister andre.schuetzenmeister@roche.com
| Package: | RIbench |
| Type: | Package |
| Version: | 1.0.2 |
| Date: | 2022-11-25 |
| License: | GPL (>=3) |
| LazyLoad: | yes |
Ammer, T., Schuetzenmeister, A., Prokosch, HU., Zierk, J., Rank, C.M., Rauh, M. RIbench: A Proposed Benchmark for the Standardized Evaluation of Indirect Methods for Reference Interval Estimation. Clin Chem (2022) [Accepted, July 12].