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ROCt (version 0.9.5)

ROCt-package:

Description

Compute ROC curve and expected utility for medical decision making, with and without censoring.

Arguments

Details

Package:
ROCt
Type:
Package
Version:
0.9.5
Date:
2017-02-17
License:
GPL (>=2)
LazyLoad:
yes
Several functions are available:
crude.ROCt
This function allows the estimation of a crude time-dependent ROC curve,
\( \mbox{ } \)
respecting the definition proposed by Heagerty et al. (2000).
net.ROCt
This function allows the estimation of net time-dependent ROC curve, i.e.
\( \mbox{ } \)
when the only cause of death is due to the disease.
EUt
The expected utility theory allows the estimation of optimal
cut-of for medical decision making.
AUC
This function computes the area under ROC curve using the trapezoidal rule
\( \mbox{ } \)
based on two vectors of sensitivities and specificities.
adjusted.ROC
This function allows for the estimation of ROC curve by taking into account possible
\( \mbox{ } \)
confounding factors (IPW or placement values estimators).
adjusted.ROCt
This function allows for the estimation of time-dependent ROC curve by taking
\( \mbox{ } \)
into account possible confounding factors (IPW estimator).

References

Heagerty PJ., Lumley T., Pepe MS. (2000) Time-dependent ROC Curves for Censored Survival Data and a Diagnostic Marker. Biometrics, 56, 337-344. <doi:10.1111/j.0006-341X.2000.00337.x> Lorent M., Giral M., Foucher Y. (2013) Net time-dependent ROC curves: a solution for evaluating the accuracy of a marker to predict disease-related mortality. Statistics in Medicine, 33, 2379-89. <doi:10.1002/sim.6079> Dantan E., Foucher Y., Lorent M., Giral M., Tessier P. (2016) Optimal threshold estimator of a prognostic marker by maximizing a time-dependent expected utility function for a patient-centered stratified medicine. Statistical Methods in Medical Research, 0, 1-13. <doi:10.1177/ 0962280216671161> Le Borgne F. et al. (2017) Standardized and weighted time-dependent ROC curves to evaluate the intrinsic prognostic capacities of a marker by taking into account confounding factors. Manuscript submitted.