smryStats1
) has 2000 cases and 2000 controls. The replication study (smryStats2
) has 1000 cases and 1000 controls. The SNP number is 10,000. The disease pravalence is 1%. Minor allele frequencies are from U(0.05, 0.5), and log-odds ratio are from 0.95N(0,1)+0.05N(0, 0.04). The ground-truth parameters for each SNP are in param
.
data(smryStats1)
data(smryStats2)
data(param)
SNP: SNP ID
F_A: Allele frequency in case group
F_U: Allele frequency in control group
Z: Z value from log-odds ratio test
P: P value
OR: Odds ratio
SE: Standard error of log(OR)
RRate
repRateEst
,
SEest
,
repSampleSizeRR
,
repSampleSizeRR2
,
HLtest