baseLineVar

This function returns the base line variability as a function of the

Application of 'RaceID' allows inference of cell types and prediction of lineage trees by the 'StemID2' algorithm (Herman, J.S., Sagar, Grun D. (2018) <DOI:10.1038/nmeth.4662>). 'VarID2' is part of this package and allows quantification of biological gene expression noise at single-cell resolution (Rosales-Alvarez, R.E., Rettkowski, J., Herman, J.S., Dumbovic, G., Cabezas-Wallscheid, N., Grun, D. (2023) <DOI:10.1186/s13059-023-02974-1>).

Dominic Grc3<bc>n

RaceID

Identification of Cell Types, Inference of Lineage Trees, and
Prediction of Noise Dynamics from Single-Cell RNA-Seq Data

Dominic Grün

baseLineVar function

<dl><dt>x</dt>
<dd>mean expression. The corresponding corrected variance is returned.</dd>
<dt>y</dt>
<dd>object returned by <code>compNoise</code>, <code>noiseBaseFit</code>, <code>pruneKnn</code> or <code>fitBackVar</code>. Depending on the input the funtion returns either
the background variability (for <code>pruneKnn</code> or <code>fitBackVar</code>) or the base line variability.</dd></dl>

Arguments

Baseline gene expression variability — baseLineVar

<dl>

<dt>x</dt>
<dd>mean expression. The corresponding corrected variance is returned.</dd>


<dt>y</dt>
<dd>object returned by <code>compNoise</code>, <code>noiseBaseFit</code>, <code>pruneKnn</code> or <code>fitBackVar</code>. Depending on the input the funtion returns either
the background variability (for <code>pruneKnn</code> or <code>fitBackVar</code>) or the base line variability.</dd>

</dl>

baseLineVar: Baseline gene expression variability

Description

Usage

Value

Arguments

Examples