postfntb

Non-normalized negative log posterior probability with a negative binomial likelihood and Cauchy prior.

Application of 'RaceID' allows inference of cell types and prediction of lineage trees by the 'StemID2' algorithm (Herman, J.S., Sagar, Grun D. (2018) <DOI:10.1038/nmeth.4662>). 'VarID2' is part of this package and allows quantification of biological gene expression noise at single-cell resolution (Rosales-Alvarez, R.E., Rettkowski, J., Herman, J.S., Dumbovic, G., Cabezas-Wallscheid, N., Grun, D. (2023) <DOI:10.1186/s13059-023-02974-1>).

Dominic Grc3<bc>n

RaceID

Identification of Cell Types, Inference of Lineage Trees, and
Prediction of Noise Dynamics from Single-Cell RNA-Seq Data

Dominic Grün

postfntb function

<dl><dt>eps</dt>
<dd>Positive real number. Residual (biological) noise.</dd>
<dt>z</dt>
<dd>Vector of integer number greater or equal zero. Transcript counts.</dd>
<dt>x0</dt>
<dd>Real number. Location parameter.</dd>
<dt>gamma</dt>
<dd>Positive real number. Scale parameter.</dd>
<dt>mu</dt>
<dd>Positive real number. Mean expression.</dd>
<dt>rt</dt>
<dd>Positive real number. Technical noise parameter. See help(fitGammaRt).</dd></dl>

Arguments

Posterior probability — postfntb

<dl>

<dt>eps</dt>
<dd>Positive real number. Residual (biological) noise.</dd>


<dt>z</dt>
<dd>Vector of integer number greater or equal zero. Transcript counts.</dd>


<dt>x0</dt>
<dd>Real number. Location parameter.</dd>


<dt>gamma</dt>
<dd>Positive real number. Scale parameter.</dd>


<dt>mu</dt>
<dd>Positive real number. Mean expression.</dd>


<dt>rt</dt>
<dd>Positive real number. Technical noise parameter. See help(fitGammaRt).</dd>

</dl>

postfntb: Posterior probability

Description

Usage

Value

Arguments