Sample.Size (version 1.0)

SampleSize_OptimalDesign-package: Sample size calculation

Description

Computes the required sample size using the optimal designs with multiple constraints proposed in Mayo et al.(2010). This optimal method is designed for two-arm, randomized phase II clinical trials, and the required sample size can be optimized either using fixed or flexible randomization allocation ratios.

Details

Package:

SampleSize_OptimalDesign

Type:

Package

Version:

1.0

Date:

2013-12-03

License:

GPL-2

Examples

Sample.Size(0.3, 0.6, 0.15, 0.15, 0.15, Allratio_c = 1, Allratio_e = 3)
Sample.Size(0.3, 0.6, 0.15, 0.15, 0.15)