addImputedScore: Calculate imputed expression values
Description
Uses L1-constrained linear models (LASSO) to impute single cell gene
expression values.
Usage
addImputedScore(object, genes.use = NULL, genes.fit = NULL, s.use = 20, do.print = FALSE, gram = TRUE)
Arguments
genes.use
A vector of genes (predictors) that can be used for
building the LASSO models.
genes.fit
A vector of genes to impute values for
s.use
Maximum number of steps taken by the algorithm (lower values
indicate a greater degree of smoothing)
do.print
Print progress (output the name of each gene after it has
been imputed).
gram
The use.gram argument passed to lars
Value
Returns a Seurat object where the imputed values have been added to
object@data