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Seurat (version 1.2.1)

diff.t.test: Differential expression testing using Student's t-test

Description

Identify differentially expressed genes between two groups of cells using the Student's t-test

Usage

diff.t.test(object, cells.1, cells.2, genes.use = NULL, thresh.use = log(2))

Arguments

object
Seurat object
cells.1
Group 1 cells
cells.2
Group 2 cells
genes.use
Genes to test. Default is to use all genes.
thresh.use
Limit testing to genes which show, on average, at least X-fold difference (log-scale) between the two groups of cells.

Increasing thresh.use speeds up the function, but can miss weaker signals.

Value

Returns a p-value ranked matrix of putative differentially expressed genes.