diffExp.test: Likelihood ratio test for zero-inflated data
Description
Identifies differentially expressed genes between two groups of cells using
the LRT model proposed in Mcdavid et al, Bioinformatics, 2011
Usage
diffExp.test(object, cells.1, cells.2, genes.use = NULL, thresh.use = log(2))
Arguments
genes.use
Genes to test. Default is to use all genes.
thresh.use
Limit testing to genes which show, on average, at least
X-fold difference (log-scale) between the two groups of cells.Increasing thresh.use speeds up the function, but can miss weaker signals.
Value
Returns a p-value ranked matrix of putative differentially expressed
genes.