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Signac (version 1.10.0)

AlleleFreq: Compute allele frequencies per cell

Description

Collapses allele counts for each strand and normalize by the total number of counts at each nucleotide position.

Usage

AlleleFreq(object, ...)

# S3 method for default AlleleFreq(object, variants, ...)

# S3 method for Assay AlleleFreq(object, variants, ...)

# S3 method for Seurat AlleleFreq(object, variants, assay = NULL, new.assay.name = "alleles", ...)

Value

Returns a Seurat object with a new assay containing the allele frequencies for the informative variants.

Arguments

object

A Seurat object, Assay, or matrix

...

Arguments passed to other methods

variants

A character vector of informative variants to keep. For example, c("627G>A","709G>A","1045G>A","1793G>A").

assay

Name of assay to use

new.assay.name

Name of new assay to store variant data in