Effects of altering serotonin levels on social interactions of mice
A data frame with 48 observations on the following 3 variables.
Contacts
Number of social contacts the mouse had during the experiment
Sex
F
=female or M
=male
Genotype
Minus
, Mixed
, or Plus
(see description below)
Serotonin is a chemical that influences mood balance in humans. But how does it affect mice? Scientists genetically altered mice by "knocking out" the expression of a gene, tryptophan hydroxylase 2 (Tph2), that regulates serotonin production. With careful breeding, the scientists produced three types of mice that we label as ``Minus'' for Tph2-/-, ``Plus'' for Tph2+/+, ``Mixed'' for Tph2+/-. The variable Genotype records Minus/Plus/Mixed. The variable Contacts is the number of social contacts that a mouse had with other mice during an experiment and the variable Sex is ``M'' for males and ``F'' for females.