Calculation of the unsigned network adjacency from expression data. The restricted set of parameters for this function should allow a faster and less memory-hungry calculation.
unsignedAdjacency(
datExpr,
datExpr2 = NULL,
power = 6,
corFnc = "cor", corOptions = "use = 'p'")
expression data. A data frame in which columns are genes and rows ar samples. Missing values are ignored.
optional specification of a second set of expression data. See details.
soft-thresholding power for network construction.
character string giving the correlation function to be used for the adjacency
calculation. Recommended choices are "cor"
and "bicor"
, but other functions can be used as
well.
character string giving further options to be passed to the correlation function
Adjacency matrix of dimensions n*n
, where n
is the number of genes in datExpr
.
The correlation function will be called with arguments datExpr, datExpr2
plus any extra
arguments given in corOptions
. If datExpr2
is NULL
,
the standard correlation functions will calculate the corelation of columns in datExpr
.
Bin Zhang and Steve Horvath (2005) "A General Framework for Weighted Gene Co-Expression Network Analysis", Statistical Applications in Genetics and Molecular Biology: Vol. 4: No. 1, Article 17