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WGCNA (version 1.73)

alignExpr: Align expression data with given vector

Description

Multiplies genes (columns) in given expression data such that their correlation with given reference vector is non-negative.

Usage

alignExpr(datExpr, y = NULL)

Value

A data frame containing the aligned expression data, of the same dimensions as the input data frame.

Arguments

datExpr

expression data to be aligned. A data frame with columns corresponding to genes and rows to samples.

y

reference vector of length equal the number of samples (rows) in datExpr

Author

Steve Horvath and Peter Langfelder

Details

The function basically multiplies each column in datExpr by the sign of its correlation with y. If y is not given, the first column in datExpr will be used as the reference vector.