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WGCNA (version 1.73)

hubGeneSignificance: Hubgene significance

Description

Calculate approximate hub gene significance for all modules in network.

Usage

hubGeneSignificance(datKME, GS)

Value

A vector whose entries are the hub gene significances for each module.

Arguments

datKME

a data frame (or a matrix-like object) containing eigengene-based connectivities of all genes in the network.

GS

a vector with one entry for every gene containing its gene significance.

Author

Steve Horvath

Details

In datKME rows correspond to genes and columns to modules.

References

Dong J, Horvath S (2007) Understanding Network Concepts in Modules, BMC Systems Biology 2007, 1:24