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abd (version 0.2-8)

LiverPreparation: Liver Preparation

Description

The unbound fraction of taurocholate for each of five concentrations of administered taurocholate.

Arguments

Format

A data frame with 5 observations on the following 2 variables.
concentration
a numeric vector
unbound.fraction
a numeric vector

Source

Smallwood, R.H., D.J. Morgan, G.W. Mihaly, and R.A. Smallwood. 1998. Effect of a protein binding change on unbound and total plasma concentrations for drugs of intermediate hepatic extraction. Journal of Pharmacokinetics and Pharmacodynamics 16:397-411.

References

http://www.ncbi.nlm.nih.gov/pubmed/3199317

Examples

Run this code
str(LiverPreparation)
xyplot(unbound.fraction ~ concentration, LiverPreparation)

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