Metadata Holding Grading Criteria for NCI-CTCAEv5
atoxgr_criteria_ctcv5
An object of class tbl_df
(inherits from tbl
, data.frame
) with 37 rows and 13 columns.
This metadata has its origin in the ADLB Grading Spec Excel file which ships with {admiral}
and can be accessed using system.file("adlb_grading/adlb_grading_spec.xlsx", package = "admiral")
in sheet = "NCICTCAEv5".
The dataset contained in there has the following columns:
SOC
: variable to hold the SOC of the lab test criteria.
TERM
: variable to hold the term describing the criteria applied to a particular lab test,
eg. 'Anemia' or 'INR Increased'. Note: the variable is case insensitive.
Grade 1
: Criteria defining lab value as Grade 1.
Grade 2
: Criteria defining lab value as Grade 2.
Grade 3
: Criteria defining lab value as Grade 3.
Grade 4
: Criteria defining lab value as Grade 4.
Grade 5
: Criteria defining lab value as Grade 5.
Definition
: Holds the definition of the lab test abnormality.
GRADE_CRITERIA_CODE
: variable to hold code that creates grade based on defined criteria.
SI_UNIT_CHECK
: variable to hold unit of particular lab test. Used to check against input data
if criteria is based on absolute values.
VAR_CHECK
: List of variables required to implement lab grade criteria. Use to check against
input data.
DIRECTION
: variable to hold the direction of the abnormality of a particular lab test
value. 'L' is for LOW values, 'H' is for HIGH values. Note: the variable is case insensitive.
COMMENT
: Holds any information regarding rationale behind implementation of grading criteria.
Note: Variables SOC
, TERM
, Grade 1
, Grade 2
,Grade 3
,Grade 4
,Grade 5
, Definition
are from the source document on NCI-CTC website defining the grading criteria.
Common Terminology Criteria for Adverse Events (CTCAE)v5.0
From these variables only 'TERM' is used in the {admiral}
code, the rest are for information and
traceability only.
Other metadata:
atoxgr_criteria_ctcv4
,
atoxgr_criteria_daids
,
country_code_lookup
,
dose_freq_lookup