GroupSequentialDesignSurvival-class

<p>Group-sequential designs for time-to-event-endpoints are a subclass of both
<code>TwoStageDesignSurvival</code> and <code>GroupSequentialDesign</code>.</p>

Optimize one or two-arm, two-stage designs for clinical trials with
respect to several implemented objective criteria or custom objectives.
Optimization under uncertainty and conditional (given stage-one outcome)
constraints are supported.
See Pilz et al. (2019) <doi:10.1002/sim.8291> and
Kunzmann et al. (2021) <doi:10.18637/jss.v098.i09> for details.

Maximilian Pilz

adoptr

Adaptive Optimal Two-Stage Designs

Kevin Kunzmann

Jan Meis

Nico Bruder

GroupSequentialDesignSurvival-class function

Group-sequential two-stage designs for time-to-event-endpoints — GroupSequentialDesignSurvival-class

Group-sequential two-stage designs for time-to-event-endpoints

GroupSequentialDesignSurvival-class: Group-sequential two-stage designs for time-to-event-endpoints

Description

Arguments

See Also