agRee (version 0.5-3)

agree.sdd: Smallest Detectable Difference

Description

Obtain confidence interval and point estimate of the smallest detectable difference (SDD).

Usage

agree.sdd(ratings, conf.level=0.95, NAaction=c("fail", "omit"))

Arguments

ratings

a matrix of observations with one subject per row and one rater per column.

conf.level

confidence level of the interval. The default is 0.95.

NAaction

a character string specifying what should happen when the data contain NAs. It must be one of "fail" and "omit" and may be abbreviated. The default is "fail" that causes the function to print an error message and terminate if there are any incomplete observations. If it is "omit", then the entire row(s) containing incomplete observation(s) will be deleted.

Value

Point estimate of the SDD and lower and upper bounds of the confidence interval.

Details

The calculation is based on one-way random-effects ANOVA and the details can be found in Baumgartner et al. (2015).

References

Richard Baumgartner, Dai Feng and Aniket Joshi (2015) Determination of smallest detectable difference for PET tracers using test-retest data: application in receptor occupancy studies (under review)

Examples

# NOT RUN {
  data(petVT)
  agree.sdd(petVT$cerebellum)
# }