Provides methods for high-throughput adaptive immune receptor repertoire sequencing (AIRR-Seq; Rep-Seq) analysis. In particular, immunoglobulin (Ig) sequence lineage reconstruction, lineage topology analysis, diversity profiling, amino acid property analysis and gene usage. Citations: Gupta and Vander Heiden, et al (2017) tools:::Rd_expr_doi("10.1093/bioinformatics/btv359"), Stern, Yaari and Vander Heiden, et al (2014) tools:::Rd_expr_doi("10.1126/scitranslmed.3008879").
Maintainer: Susanna Marquez susanna.marquez@yale.edu
Authors:
Namita Gupta namita.gupta@yale.edu
Nima Nouri nima.nouri@yale.edu
Ruoyi Jiang ruoyi.jiang@yale.edu
Julian Zhou julian.zhou@bulldogs.yale.edu
Kenneth Hoehn kenneth.hoehn@yale.edu
Jason Vander Heiden jason.vanderheiden@gmail.com
Steven Kleinstein steven.kleinstein@yale.edu [copyright holder]
Other contributors:
Daniel Gadala-Maria daniel.gadala-maria@yale.edu [contributor]
Edel Aron edel.aron@yale.edu [contributor]
Cole Jensen cole.jensen@yale.edu [contributor]
Useful links: