Calculates the average empirical distribution across all samples.
# S3 method for AffymetrixCelSet
averageQuantile(this, probes=NULL, excludeCells=NULL, ..., verbose=FALSE)
Returns a double
vector
of length N.
If NA
s are detected in a sample, these are excluded and the
approx()
function (approx
) is used to "expand"
the vector
of the remaining values so that the sorted vector
(still) have length N.
Henrik Bengtsson
This methods implements Step A2-A3 in the algorithm for quantile normalization proposed by Bengtsson et al. (2008).
[1] H. Bengtsson, R. Irizarry, B. Carvalho, & T.P. Speed. Estimation and assessment of raw copy numbers at the single locus level, Bioinformatics, 2008.
averageQuantile.list
For more information see AffymetrixCelSet
.