coef_to_liab

Coefficient to convert to the liability scale. E.g. h2_liab = coef * h2_obs.

Easy-to-use, efficient, flexible and scalable tools for analyzing
massive SNP arrays. Privé et al. (2018) <doi:10.1093/bioinformatics/bty185>.

Florian Privé

bigsnpr

Analysis of Massive SNP Arrays

Michael Blum

Hugues Aschard

Bjarni Jóhann Vilhjálmsson

coef_to_liab function

<dl><dt>K_pop</dt>
<dd>Prevalence in the population.</dd>
<dt>K_gwas</dt>
<dd>Prevalence in the GWAS. You should provide this if you used
(<code>n_case + n_control</code>) as sample size. If using the effective sample size
<code>4 / (1 / n_case + 1 / n_control)</code> instead, you should keep the default
value of <code>K_gwas = 0.5</code> as the GWAS case-control ascertainment is already
accounted for in the effective sample size.</dd></dl>

Arguments

Liability scale — coef_to_liab

<dl>

<dt>K_pop</dt>
<dd>Prevalence in the population.</dd>


<dt>K_gwas</dt>
<dd>Prevalence in the GWAS. You should provide this if you used
(<code>n_case + n_control</code>) as sample size. If using the effective sample size
<code>4 / (1 / n_case + 1 / n_control)</code> instead, you should keep the default
value of <code>K_gwas = 0.5</code> as the GWAS case-control ascertainment is already
accounted for in the effective sample size.</dd>

</dl>

coef_to_liab: Liability scale

Description

Usage

Value

Arguments

Examples