bigsnpr (version 1.9.11)

snp_gc: Genomic Control

Description

Genomic Control

Usage

snp_gc(gwas)

Value

A ggplot2 object. You can plot it using the print method. You can modify it as you wish by adding layers. You might want to read this chapter

to get more familiar with the package ggplot2.

Arguments

gwas

A mhtest object with the p-values associated with each SNP. Typically, the output of big_univLinReg, big_univLogReg or snp_pcadapt.

References

Devlin, B., & Roeder, K. (1999). Genomic control for association studies. Biometrics, 55(4), 997-1004.

Examples

set.seed(9)

test <- snp_attachExtdata()
G <- test$genotypes
y <- rnorm(nrow(G))

gwas <- big_univLinReg(G, y)
snp_qq(gwas)
gwas_gc <- snp_gc(gwas) # change attr(gwas_gc, "transfo")

snp_qq(gwas_gc)
# The next plot should be prettier with a real dataset
snp_manhattan(gwas_gc,
              infos.chr = test$map$chromosome,
              infos.pos = test$map$physical.pos)

p <- snp_qq(gwas_gc) + ggplot2::aes(text = asPlotlyText(test$map))
if (FALSE) plotly::ggplotly(p, tooltip = "text")