Simulation of deterministic and stochastic biochemical reaction
networks using Petri Nets
Description
bioPN is a package suited to perform simulation of deterministic and stochastic systems of biochemical reaction
networks.
Models are defined using a subset of Petri Nets, in a way that is close at how chemical reactions
are defined.
For deterministic solutions, bioPN creates the associated system of differential equations "on the fly", and
solves it with a Runge Kutta Dormand Prince 45 explicit algorithm.
For stochastic solutions, bioPN offers variants of Gillespie algorithm, or SSA.
For hybrid deterministic/stochastic,
it employs the Haseltine and Rawlings algorithm, that partitions the system in fast and slow reactions.
bioPN algorithms are developed in C to achieve adequate performance.