bpp-package: Tools for Computation of Bayesian Predictive Power for a Normally Distributed Endpoint with Known Variance
Description
Implements functions to update Bayesian Predictive Power Computations after not stopping a clinical trial at an interim analysis, whether blinded or unblinded, for a Normally distributed endpoint with known variance, with a prominent example being the hazard ratio.
Rufibach, K., Jordan, P., Abt, M. (2016a).
Sequentially Updating the Likelihood of Success of a Phase 3 Pivotal Time-to-Event Trial based on Interim Analyses or External Information.
J. Biopharm. Stat., 26(2), 191--201.
Rufibach, K., Burger, H.U., Abt, M. (2016b).
Bayesian Predictive Power: Choice of Prior and some Recommendations for its Use as Probability of Success in Drug Development.
Pharm. Stat., 15, 438--446.
