Functions for Toxicokinetic-Toxidynamic (TKTD) models
ODE solver applied to IT-GUTS model
ODE solver applied to SD-GUTS model
brk_toxFun_damage1(exposure, kin, kout)brk_toxFun_survival1(damage, alpha1, alpha2, alpha3)
brk_toxFun_survival2(damage, LC50, slope)
brk_survIT(time, Cw, listParameters)
brk_survSD(time, Cw, listParameters)
exposure level of individual
parameter describing the intake rate of the element
parameter describing the excretion rate of the element
damage level on which the survival model is going to be applied
parameter describing the natural background death mortality rate
parameter describing the killing rate of the element on individual
exponential parameter describing the killing rate of the element on individual
parameter describing the lethal concentration for 50% of the population
parameter describing the slope of the curve
vector of time of the exposure profile
vector of concentration of the exposure profile
A list of parameter for the SD model