flagSampledParameterRows

Flag all parameter rows that have at least one parameter out of the specified range
or that have a non positive definite OMEGA or SIGMA matrix.

internal

A generic, easy-to-use and expandable implementation of a
pharmacokinetic (PK) / pharmacodynamic (PD) model based on the S4
class system. This package allows the user to read/write a
pharmacometric model from/to files and adapt it further on the fly in
the R environment. For this purpose, this package provides an
intuitive API to add, modify or delete equations, ordinary
differential equations (ODE's), model parameters or compartment
properties (like infusion duration or rate, bioavailability and
initial values). Finally, this package also provides a useful export
of the model for use with simulation packages 'rxode2' and 'mrgsolve'.
This package is designed and intended to be used with package
'campsis', a PK/PD simulation platform built on top of 'rxode2' and
'mrgsolve'.

Nicolas Luyckx

campsismod

Generic Implementation of a PK/PD Model

flagSampledParameterRows function

<dl><dt>table</dt>
<dd>a data frame returned by <code>sampleMore</code></dd>
<dt>minMax</dt>
<dd>a data frame with min, max values for each parameter</dd>
<dt>settings</dt>
<dd>replication settings</dd>
<dt>parameters</dt>
<dd>double array parameters to check for positive definiteness</dd></dl>

Arguments

Flag all parameter rows that have at least one parameter out of the specified range
or that have a non positive definite OMEGA or SIGMA matrix. — flagSampledParameterRows

<dl>

<dt>table</dt>
<dd>a data frame returned by <code>sampleMore</code></dd>


<dt>minMax</dt>
<dd>a data frame with min, max values for each parameter</dd>


<dt>settings</dt>
<dd>replication settings</dd>


<dt>parameters</dt>
<dd>double array parameters to check for positive definiteness</dd>

</dl>

flagSampledParameterRows: Flag all parameter rows that have at least one parameter out of the specified range or that have a non positive definite OMEGA or SIGMA matrix.

Description

Usage

Arguments