Estimate and remove background signal using anti-genomic background probes
Usage
bgAdjust(dat, copy=TRUE)
Arguments
dat
a TilingFeatureSet
copy
Only relevant when using disk-backed objects. If TRUE a copy will be made leaving the original object (dat) unchanged. The input object will not be preserved if copy=FALSE
Value
a TilingFeatureSet
Details
Background signal removal using a modified version of the RMA convolution model. The background signal level is estimated within GC-strata using anti-genomic background probes.