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charm (version 2.18.0)

bgAdjust: Remove background

Description

Estimate and remove background signal using anti-genomic background probes

Usage

bgAdjust(dat, copy=TRUE)

Arguments

dat
a TilingFeatureSet
copy
Only relevant when using disk-backed objects. If TRUE a copy will be made leaving the original object (dat) unchanged. The input object will not be preserved if copy=FALSE

Value

a TilingFeatureSet

Details

Background signal removal using a modified version of the RMA convolution model. The background signal level is estimated within GC-strata using anti-genomic background probes.

Examples

Run this code
# See normalizeBetweenSamples

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