coin (version 1.0-24)

ocarcinoma: Ovarian Carcinoma

Description

Survival times of 35 women suffering ovarian carcinoma at stadium II and IIA.

Usage

data("ocarcinoma")

source

Thomas R. Fleming, Judith R. O'Fallon, Peter C. O'Brien & David P. Harrington (1980). Modified Kolmogorov-Smirnov test procedures with applications to arbitrarily censored data. Biometrics 36, 607--625.

Thomas R. Fleming, Stephanie J. Green & David P. Harrington (1984). Considerations of monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials 5, 55--66.

Details

Data from Fleming et al. (1980, 1984), reanalysed in Schumacher and Schulgen (2002).

References

Martin Schumacher & Gabi Schulgen (2002), Methodik klinischer Studien: Methodische Grundlagen der Planung, Durchf"uhrung und Auswertung. Springer, Heidelberg.

Examples

### logrank test with exact two-sided p-value
  lrt <- surv_test(Surv(time, event) ~ stadium, data = ocarcinoma,
                   distribution = "exact")

  ### the test statistic
  statistic(lrt)

  ### p-value
  pvalue(lrt)