install.packages('crmPack')LogisticIndepBeta model
model and efficacy responses using ModelEff model class
with DLE and efficacy samples.It contain all slots in
RuleDesign and TDsamplesDesign class objectLogisticIndepBeta model
model and efficacy responses using ModelEff model class
without DLE and efficacy samples. It contain all slots in
RuleDesign and TDDesign class objectModelTox
class and the efficacy model from ModelEff class
(except EffFlexi class). It contains all slots from
GeneralSimulations and PseudoSimulations object.
In comparison to the parent class PseudoSimulations,
it contains additional slots to
capture the dose-efficacy curve and the sigma2 estimates.ModelPseudoModelTox
class object. It contains all slots from GeneralSimulations object.
Additional slots fit and stopReasons compared to the general class
GeneralSimulations.ModelTox
class and the efficacy model from EffFlexi class
It contains all slots from
GeneralSimulations, PseudoSimulations
and PseudoDualSimulations object.
In comparison to the parent class PseudoDualSimulations,
it contains additional slots to
capture the sigma2betaW estimates.RuleDesign,
objects of this class contain:TDDesign where model used are of
ModelTox class object and no samples are involved.TDsamplesDesign where model used are of
ModelTox class object DLE samples are also usedModelEff class
with samplesEffFlexi class object) when new data
or new observations of responses are available and added in.ModelTox class model with samplesDualResponsesDesign where DLEmodel used are of
ModelTox class object and efficacy model used are of ModelEff
class object. In addition, no DLE and efficacy samples are involved or generated in the simulation
processDualResponsesSamplesDesign where DLEmodel
used are of
ModelTox class object and efficacy model used are of
ModelEff
class object (special case is EffFlexi class model object).
In addition, DLE and efficacy samples are involved or generated in the simulation
process