IncrementsNumDoseLevels-class

.IncrementsNumDoseLevels

Increments control based on number of dose levels

classes

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of CRM Designs

Wai Yin Yeung

Giuseppe Palermo

Thomas Jaki

IncrementsNumDoseLevels-class function

<dl>
<dt><code>maxLevels</code></dt>
<dd>scalar positive integer for the number of maximum 
dose levels to increment for the next dose. It defaults to 1, 
which means that no dose skipping is allowed - the next dose 
can be maximum one level higher than the current dose.</dd></dl>

Slots

Increments control based on number of dose levels — IncrementsNumDoseLevels-class

<dl>
<dt><code>maxLevels</code></dt>
<dd>scalar positive integer for the number of maximum 
dose levels to increment for the next dose. It defaults to 1, 
which means that no dose skipping is allowed - the next dose 
can be maximum one level higher than the current dose.</dd>


</dl>

IncrementsNumDoseLevels-class: Increments control based on number of dose levels

Description

Arguments

Slots

Examples