NextBestThreePlusThree-class

.NextBestThreePlusThree

<p>Implements the classical 3+3 dose recommendation.
No input is required, hence this class has no slots.</p>

classes

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of CRM Designs

Wai Yin Yeung

Giuseppe Palermo

Thomas Jaki

NextBestThreePlusThree-class function

The class with the input for finding the next dose in target interval — NextBestThreePlusThree-class

The class with the input for finding the next dose in target interval

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NextBestThreePlusThree-class: The class with the input for finding the next dose in target interval

Description

Arguments

Examples