Simulations-class

.Simulations

This class captures the trial simulations from model based designs.
Additional slots fit and stopReasons compared to the general class
<code>GeneralSimulations</code>.

classes

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of CRM Designs

Wai Yin Yeung

Giuseppe Palermo

Thomas Jaki

Simulations-class function

<dl>
<dt><code>fit</code></dt>
<dd>list with the final fits</dd></dl>
<dt><code>stopReasons</code></dt>
<dd>list of stopping reasons for each simulation run</dd>

Slots

Class for the simulations output from model based designs — Simulations-class

<dl>
<dt><code>fit</code></dt>
<dd>list with the final fits</dd>


<dt><code>stopReasons</code></dt>
<dd>list of stopping reasons for each simulation run</dd>


</dl>

Simulations-class: Class for the simulations output from model based designs

Description

Arguments

Slots