setSeed

This is basically copied from simulate.lm

programming

Implements a wide range of model-based dose
escalation designs, ranging from classical and modern continual
reassessment methods (CRMs) based on dose-limiting toxicity endpoints to
dual-endpoint designs taking into account a biomarker/efficacy outcome. The
focus is on Bayesian inference, making it very easy to setup a new design
with its own JAGS code. However, it is also possible to implement 3+3
designs for comparison or models with non-Bayesian estimation. The whole
package is written in a modular form in the S4 class system, making it very
flexible for adaptation to new models, escalation or stopping rules.

Daniel Sabanes Bove

crmPack

Object-Oriented Implementation of CRM Designs

Wai Yin Yeung

Giuseppe Palermo

Thomas Jaki

setSeed function

<dl><dt>seed</dt>
<dd>an object specifying if and how the random number generator
should be initialized (&#8220;seeded&#8221;). Either <code>NULL</code> (default) or an
integer that will be used in a call to <code><a href="/link/set.seed?package=crmPack&version=1.0.6" data-mini-rdoc="crmPack::set.seed">set.seed</a></code> before
simulating the response vectors. If set, the value is saved as the
<code>seed</code> slot of the returned object. The default, <code>NULL</code> will
not change the random generator state.</dd></dl>

Arguments

Daniel Sabanes Bove <a href="/link/sabanesd%40roche.com?package=crmPack&version=1.0.6" data-mini-rdoc="crmPack::sabanesd@roche.com">sabanesd@roche.com</a>

Author

Helper function to set and save the RNG seed — setSeed

<dl>

<dt>seed</dt>
<dd>an object specifying if and how the random number generator
should be initialized (&#8220;seeded&#8221;). Either <code>NULL</code> (default) or an
integer that will be used in a call to <code><a href='https://rdrr.io/r/base/Random.html'>set.seed</a></code> before
simulating the response vectors. If set, the value is saved as the
<code>seed</code> slot of the returned object. The default, <code>NULL</code> will
not change the random generator state.</dd>

</dl>

Daniel Sabanes Bove <a href='mailto:sabanesd@roche.com'>sabanesd@roche.com</a>

setSeed: Helper function to set and save the RNG seed

Description

Usage

Value

Arguments

Author