Drug properties that have been experimentally proven
drug_exp_prop()a tibble with the following variables:
Name of the property.
Drug properties that have been experimentally proven.
Reference to the source of this experimental data.
drugbank id
The following experimental properties are provided:
The experimentally determined aqueous solubility of the molecule.
Protein formula of Biotech drugs
Protein weight of Biotech drugs.
The experimentally determined temperature at which the drug molecule changes from solid to liquid at atmospheric temperature.
The experimentally determined temperature at which the drug molecule changes from liquid to gas at atmospheric temperature.
The ability of a molecule to repel water rather than absorb or dissolve water.
The pH value at which the net electric charge of a molecule is zero.
A continuous line of heterogenous human epithelial colorectal adenocarcinoma cells, CAC02 cells are employed as a model of human intestinal absorption of various drugs and compounds. CAC02 cell permeability is ultimately an assay to measure drug absorption.
The experimentally determined pka value of the molecule
The experimentally determined partition coefficient (LogP) based on the ratio of solubility of the molecule in 1-octanol compared to water.
The intrinsic solubility of a given compound is the concentration in equilibrium with its solid phase that dissolves into solution, given as the natural logarithm (LogS) of the concentration.
The property to spontaneously emit particles (alpha, beta, neutron) or radiation (gamma, K capture), or both at the same time, from the decay of certain nuclides.