The directPA-package is designed for analysing pathways in experiments with multiple perturbations. The combination effects of different treatments are tested by rotating polar coordinates in two-dimentional space when the experiment contains two perturbations and corresponding controls, or spherical coordinates in three-dimensional space when the experiment contains three perturbations and corresponding controls.
Pengyi Yang <yangpy7@gmail.com> & Ellis Patrick <epatrick87@gmail.com>
| Package: | directPA |
| Type: | Package |
| Version: | 1.5.1 |
| License: | GPL-3 |
Pengyi Yang, Ellis Patrick, Shi-Xiong Tan, Daniel J. Fazakerley, James Burchfield, Christopher Gribben, Matthew J. Prior, David E. James, Yee Hwa Yang, Direction pathway analysis of large-scale proteomics data reveals novel features of the insulin action pathway, Bioinformatics, 30(6), 808-814, 2014.