A small example database subset from Laserson and Vigneault et al, 2014.
ExampleAirr
A data.frame with the following AIRR style columns:
sequence_id
: Sequence identifier
sequence_alignment
: IMGT-gapped observed sequence.
germline_alignment_d_mask
: IMGT-gapped germline sequence with N, P and
D regions masked.
v_call
: V region allele assignments.
v_call_genotyped
: TIgGER corrected V region allele assignment.
d_call
: D region allele assignments.
j_call
: J region allele assignments.
junction
: Junction region sequence.
junction_length
: Length of the junction region in nucleotides.
np1_length
: Combined length of the N and P regions proximal
to the V region.
np2_length
: Combined length of the N and P regions proximal
to the J region.
sample
: Sample identifier. Time in relation to vaccination.
isotype
: Isotype assignment.
duplicate_count
: Copy count (number of duplicates) of the sequence.
clone_id
: Change-O assignment clonal group identifier.
Laserson U and Vigneault F, et al. High-resolution antibody dynamics of vaccine-induced immune responses. Proc Natl Acad Sci USA. 2014 111:4928-33.
ExampleDbChangeo ExampleClones