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dowser (version 2.2.0)

ExampleAirr: Example AIRR database

Description

A small example database subset from Laserson and Vigneault et al, 2014.

Usage

ExampleAirr

Arguments

Format

A data.frame with the following AIRR style columns:

  • sequence_id: Sequence identifier

  • sequence_alignment: IMGT-gapped observed sequence.

  • germline_alignment_d_mask: IMGT-gapped germline sequence with N, P and D regions masked.

  • v_call: V region allele assignments.

  • v_call_genotyped: TIgGER corrected V region allele assignment.

  • d_call: D region allele assignments.

  • j_call: J region allele assignments.

  • junction: Junction region sequence.

  • junction_length: Length of the junction region in nucleotides.

  • np1_length: Combined length of the N and P regions proximal to the V region.

  • np2_length: Combined length of the N and P regions proximal to the J region.

  • sample: Sample identifier. Time in relation to vaccination.

  • isotype: Isotype assignment.

  • duplicate_count: Copy count (number of duplicates) of the sequence.

  • clone_id: Change-O assignment clonal group identifier.

References

  1. Laserson U and Vigneault F, et al. High-resolution antibody dynamics of vaccine-induced immune responses. Proc Natl Acad Sci USA. 2014 111:4928-33.

See Also

ExampleDbChangeo ExampleClones