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drc (version 1.5-5)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

28,339

Version

1.5-5

License

GPL (>= 2)

Maintainer

Christian Ritz

Last Published

February 15th, 2017

Functions in drc (1.5-5)

CRS.4a

The Cedergreen-Ritz-Streibig model
CRS.5a

The Cedergreen-Ritz-Streibig model
lnormal

Log-normal dose-response model
BC.5

The Brain-Cousens hormesis models
AR

Asymptotic regression model
drm

Fitting dose-response models
cedergreen

The Cedergreen-Ritz-Streibig model
W1.4

The four-parameter Weibull functions
confint.drc

Confidence Intervals for model parameters
diagnostics

Information on estimation
S.capricornutum

Effect of cadmium on growth of green alga
beetGrowth

Example of plant growth curve from Covarelli and Onofri (1998)
auxins

Effect of technical grade and commerecially formulated auxin herbicides
braincousens

The Brain-Cousens hormesis models
methionine

Weight gain for different methionine sources
MAX

Maximum mean response
compParm

Comparison of parameters
acidiq

Acifluorfen and diquat tested on Lemna minor.
SI

Comparing selectivity indices across curves
gompertzd

The derivative of the Gompertz function
gompGrowth

Gompertz growth models
fitted.drc

Extract fitted values from model
vinclozolin

Vinclozolin from AR in vitro assay
H.virescens

Mortality of tobacco budworms
LL.3

The three-parameter log-logistic function
getMeanFunctions

Display available dose-response models
drmc

Sets control arguments
O.mykiss

Test data from a 21 day fish test
EXD

Exponential decay model
isobole

Creating isobolograms
boxcox.drc

Transform-both-sides Box-Cox transformation
daphnids

Daphnia test
print.summary.drc

Printing summary of non-linear model fits
LL.2

The two-parameter log-logistic function
M.bahia

Effect of an effluent on the growth of mysid shrimp
MM

Michaelis-Menten model
vcov.drc

Calculating Variance-Covariance Matrix for objects of class 'drc'
deguelin

Deguelin applied to chrysanthemum aphis
P.promelas

Effect of sodium pentachlorophenate on growth of fathead minnow
predict.drc

Prediction
RScompetition

Competition between two biotypes
colFct

Collapse of levels
comped

Comparison of effective dose values
residuals.drc

Extracting residuals from model
logistic

The logistic (Boltzmann) model
multdrc

Fitting multiple dose-response curves
plotraw

Plotting raw dose response data.
glymet

Glyphosate and metsulfuron-methyl tested on algae.
gompertz

Mean function for the Gompertz dose-response or growth curve
LL.5

The five-parameter log-logistic function
PR

Expected or predicted response
logLik.drc

Extracting the log likelihood
W1.2

The two-parameter Weibull functions
bread.drc

Bread and meat for the sandwich
mrdrm

Model-robust dose-response modelling
leaflength

Leaf length of barley
plot.drc

Plotting fitted curves for a 'drc' or 'mrdrc' object
earthworms

Earthworms
weibull1

The Weibull functions
finney71

Example from Finney (1971)
heartrate

Heart rate baroreflexes for rabbits
LL.4

The four-parameter log-logistic function
W1.3

The three-parameter Weibull functions
mecter

Mechlorprop and terbythylazine tested on Lemna minor
richards

Richards model
spinach

Inhibition of photosynthesis
baro5

The modified baro5 function
llogistic

The log-logistic function
lettuce

Isobutylalcohol in nutrient solution in which lettuce plants were grown
searchdrc

Searching through a range of initial parameter values to obtain convergence
S.alba

Potency of two herbicides
mselect

Model selection
rdrm

Simulating a dose-response curve
mixdrc

Fitting multiple dose-response curves with random effects
update.drc

Updating and re-fitting a model
coef.drc

Extract Model Coefficients
G.aparine

Herbicide applied to Galium aparine
lepidium

Dose-response profile of degradation of agrochemical using lepidium
ED.drc

Estimating effective doses
print.drc

Printing key features
anova.drc

ANOVA for non-linear model fits
ryegrass

Effect of ferulic acid on growth of ryegrass
mdControl

Sets control arguments
secalonic

Root length
mixture

Fitting mixture models
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
summary.drc

Summarising non-linear model fits
terbuthylazin

The effect of terbuthylazin on growth rate
simDR

Simulating ED values under various scenarios