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drc (version 1.6-0)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

28,339

Version

1.6-0

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

March 24th, 2009

Functions in drc (1.6-0)

ANOVA for non-linear model fits

The Cedergreen-Ritz-Streibig model

Extract Model Coefficients

The four-parameter Weibull functions

Extract fitted values from model

Effect of sodium pentachlorophenate on growth of fathead minnow

Sets control arguments

Vinclozolin from AR in vitro assay

print.summary.drc

Printing summary of non-linear model fits

Effect of an effluent on the growth of mysid shrimp

Glyphosate and metsulfuron-methyl tested on algae.

Confidence Intervals for model parameters

Mean function for the Gompertz dose-response or growth curve

Extracting residuals from model

Fitting mixture models

Printing key features

The four-parameter log-logistic function

The modified baro5 function

The derivative of the Gompertz function

Effect of ferulic acid on growth of ryegrass

Weibull model functions

Acifluorfen and diquat tested on Lemna minor.

The Brain-Cousens hormesis models

Herbicide applied to Galium aparine

The Cedergreen-Ritz-Streibig model

Information on estimation

Effect of technical grade and commercially formulated auxin herbicides

Maximum mean response

Checking the model fot

Simulating a dose-response curve

Model selection

Simulating ED values under various scenarios

Estimating effective doses

Mortality of tobacco budworms

The five-parameter log-logistic function

The two-parameter Weibull functions

Test data from a 21 day fish test

Potency of two herbicides

Comparing selectivity indices across curves

Comparison of parameters

Transform-both-sides Box-Cox transformation

Bread and meat for the sandwich

Heart rate baroreflexes for rabbits

Weight gain for different methionine sources

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Extracting the log likelihood

Creating isobolograms

Mechlorprop and terbythylazine tested on Lemna minor

Inhibition of photosynthesis

The effect of terbuthylazin on growth rate

Expected or predicted response

Exponential decay model

The two-parameter log-logistic function

Michaelis-Menten model

Deguelin applied to chrysanthemum aphis

Comparison of effective dose values

The three-parameter Weibull functions

Leaf length of barley

The three-parameter log-logistic function

Fitting dose-response models

The log-logistic function

Example from Finney (1971)

Log-normal dose-response model

The logistic model

Plotting raw dose response data.

Fitting multiple dose-response curves with random effects

Searching through a range of initial parameter values to obtain convergence

Updating and re-fitting a model

Asymptotic regression model

S.capricornutum

Effect of cadmium on growth of green alga

Competition between two biotypes

The Brain-Cousens hormesis models

Example of plant growth curve from Covarelli and Onofri (1998)

The Cedergreen-Ritz-Streibig model

Gompertz growth models

getMeanFunctions

Display available dose-response models

Dose-response profile of degradation of agrochemical using lepidium

Model-robust dose-response modelling

Dose-response profile of degradation of agrochemical using nasturtium

Plotting fitted curves for a 'drc' or 'mrdrc' object

Summarising non-linear model fits

Calculating yield loss parameters

Calculating variance-covariance matrix for objects of class 'drc'