NKI breast cancer clinical data: Clinical and follow-up data of breast cancer patients as collected in the Dutch Cancer Institute (NKI) in Amsterdam

Description

A data frame of 295 patients with breast cancer. The included variables are

patnr: Patient identification number
d: Survival status; 1 = death; 0 = censored
tyears: Time in years until death or last follow-up
diameter: Diameter of the primary tumor
posnod: Number of positive lymph nodes
age: Age of the patient
mlratio: Estrogen level?
chemotherapy: Chemotherapy used (yes/no)
hormonaltherapy: Hormonal therapy used (yes/no)
typesurgery: Type of surgery (excision or mastectomy)
histolgrade: Histological grade (Intermediate, poorly, or well differentiated)
vasc.invasion: Vascular invasion (-, +, or +/-)
crossval.clin.class: ??
PICV: Estrogen level?

Arguments

Format

A data frame, see data.frame.

References

van't Veer LJ, Dai HY, van de Vijver MJ, He YDD, Hart AAM, Mao M, Peterse HL, van der Kooy K, Marton MJ, Witteveen AT, Schreiber GJ, Kerkhoven RM, Roberts C, Linsley PS, Bernards R \& Friend SH (2002). Gene expression profiling predicts clinical outcome of breast cancer. Nature 415, 530--536.

van de Vijver MJ, He YD, van `t Veer LJ, Dai H, Hart AAM, Voskuil DW, Schreiber GJ, Peterse JL, Roberts C, Marton MJ, Parrish M, Atsma D, Witteveen A, Glas A, Delahaye L, van der Velde T, Bartelink H, Rodenhuis S, Rutgers ET, Friend SH \& Bernards R (2002). A gene-expression signature as a predictor of survival in breast cancer. New England Journal of Medicine 347, 1999--2009.

van Houwelingen HC, Bruinsma T, Hart AAM, van't Veer LJ \& Wessels LFA (2006). Cross-validated Cox regression on microarray gene expression data. Statistics in Medicine 25, 3201--3216.