exactRankTests (version 0.7-7)

ocarcinoma: Ovarian Carcinoma

Description

Survival times of 35 women suffering ovarian carcinoma at stadium II and IIA.

Usage

data(ocarcinoma)

source

T. R. Fleming, J. R. O'Fallon, P. C. O'Brien and D. P. Harrington (1980). Modified Kolmogorov-Smirnov test procedures with applications to arbitrarily censored data. Biometrics, 36, 607--625.

T. R. Fleming, S. J. Green and D. P. Harrington (1984). Considerations of monitoring and evaluating treatment effects in clinical trials. Controlled Clinical Trials, 5, 55--66.

Details

Data from Fleming et al. (1980, 1984), reanalysed in Schumacher and Schulgen (2002).

References

M. Schumacher and G. Schulgen (2002). Methodik klinischer Studien: methodische Grundlagen der Planung, Durchf�hrung und Auswertung. Springer, Heidelberg.

Examples

data(ocarcinoma)
attach(ocarcinoma)
# compute integer valued logrank scores
logrsc <- cscores.Surv(cbind(time, cens), int=TRUE)
# the test statistic
lgT <- sum(logrsc[stadium == "II"])
# p-value
round(pperm(lgT, logrsc, m=sum(stadium=="II"), al="tw"), 4)