biasMatrix

This is a data frame with two columns and the column names are "sN", "sT".  They are the site-specific bias in total coverage for normal (control) sample and tumor (case) sample, respectively.


This is a method for Allele-specific DNA Copy Number profiling for whole-Exome sequencing data.  Given the allele-specific coverage and site biases at the variant loci, this program segments the genome into regions of homogeneous allele-specific copy number.  It requires, as input, the read counts for each variant allele in a pair of case and control samples, as well as the site biases. For detection of somatic mutations, the case and control samples can be the tumor and normal sample from the same individual.

biasMatrix: Bias Matrix

Description

Arguments