readMatrix

This is a data frame with four columns and the column names are "AN", "BN", "AT"
and "BT". They are A-allele coverage in the tumor (case) sample, B-allele coverage
in the tumor (case) sample, A-allele coverage in the normal (control) sample,
and B-allele coverage in the normal (control) sample, respectively.

This is a method for Allele-specific DNA Copy Number profiling for whole-Exome sequencing data.  Given the allele-specific coverage and site biases at the variant loci, this program segments the genome into regions of homogeneous allele-specific copy number.  It requires, as input, the read counts for each variant allele in a pair of case and control samples, as well as the site biases. For detection of somatic mutations, the case and control samples can be the tumor and normal sample from the same individual.

readMatrix: Reads Matrix

Description

Arguments