flexmix (version 2.3-19)

betablocker: Clinical Trial of Beta-Blockers

Description

22-centre clinical trial of beta-blockers for reducing mortality after myocardial infarction.

Usage

data("betablocker")

Format

A data frame with 44 observations on the following 4 variables.

Deaths

Number of deaths.

Total

Total number of patients.

Center

Number of clinical centre.

Treatment

A factor with levels Control and Treated.

References

M. Aitkin. Meta-analysis by random effect modelling in generalized linear models. Statistics in Medicine, 18, 2343--2351, 1999.

S. Yusuf, R. Peto, J. Lewis, R. Collins and P. Sleight. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Progress in Cardiovascular Diseases, 27, 335--371, 1985.

Examples

data("betablocker", package = "flexmix")
betaMix <- initFlexmix(cbind(Deaths, Total - Deaths) ~ 1 | Center,
                       data = betablocker, k = 3, nrep = 5,
                       model = FLXMRglmfix(family = "binomial",
                         fixed = ~Treatment))