rituximab


A flow cytometry dataset produced in a drug-screening project to identify agents that would enhance the anti-lymphoma activity of Rituximab, a therapeutic monoclonal antibody.  Cells were stained with anti-BrdU FITC and the DNA binding dye 7-AAD.


datasets

Robust model-based clustering using a t-mixture model with
Box-Cox transformation. Note: users should have GSL installed.
Windows users: 'consult the README file available in the inst
directory of the source distribution for necessary
configuration instructions'.

Greg Finak

flowClust

Clustering for Flow Cytometry

rituximab function

An object of class <code>flowFrame</code> with 1545 cells (rows) and the following eight variables (columns):
<dl>
   <dt>FSC.H</dt><dd>FSC-Height</dd> <dt>SSC.H</dt><dd>Side Scatter</dd> <dt>FL1.H</dt><dd>Anti-BrdU FITC</dd> <dt>FL2.H</dt><dd>Channel not used</dd> <dt>FL3.H</dt><dd>7 AAD</dd> <dt>FL1.A</dt><dd>Channel not used</dd> <dt>FL1.W</dt><dd>Channel not used</dd> <dt>Time</dt><dd>Time</dd> </dl> 

Format

Gasparetto, M., Gentry, T., Sebti, S., O'Bryan, E., Nimmanapalli, R., Blaskovich, M. A., Bhalla, K., Rizzieri, D., Haaland, P., Dunne, J. and Smith, C. (2004) Identification of compounds that enhance the anti-lymphoma activity of rituximab using flow cytometric high-content screening. <em>J. Immunol. Methods</em> <b>292</b>, 59-71.

rituximab: The Rituximab Dataset

Description

Usage

Arguments

Format

Source