data-breastcancer: Gene expression signatures for p53 mutation status in 250 breast cancer
samples
Description
Perturbations of the p53 pathway are associated with more aggressive and
therapeutically refractory tumours. We preprocessed the data using Robust
Multichip Analysis (RMA). Dataset has been truncated to the 1000 most
informative genes (as selected by Wilcoxon test statistics) to simplify
computation. The genes have been standardised to have zero mean and unit
variance (i.e. z-scored).
Usage
data(breastcancer)
Arguments
Format
A data frame with 250 observations on 1001 variables. The
first 1000 columns are numerical variables; the last column
(named code) is a factor with levels case and
control.
Details
The factor code defines whether there was a mutation in the p53
sequence (code=case) or not (code=control).