This data set contains eight ALDH2 markers and Japanese alcohlic patients (y=1) and controls (y=0). There are genotypes for 8 loci, with a prefix name (e.g., "EXON12") and a suffix for each of two alleles (".a1" and ".a2").
The eight markers loci follows the following map (base pairs)
D12S2070 | (> 450 000), |
D12S839 | (> 450 000), |
D12S821 | (\(\sim\) 400 000), |
D12S1344 | ( 83 853), |
EXON12 | ( 0), |
EXON1 | ( 37 335), |
D12S2263 | ( 38 927), |
data(aldh2)
A data frame
Koch HG, McClay J, Loh E-W, Higuchi S, Zhao J-H, Sham P, Ball D, et al (2000) Allele association studies with SSR and SNP markers at known physical distances within a 1 Mb region embracing the ALDH2 locus in the Japanese, demonstrates linkage disequilibrium extending up to 400 kb. Hum. Mol. Genet. 9:2993-2999