findLargest: Find the Entrez Gene ID corresponding to the largest statistic
Description
Most microarrays have multiple probes per gene (Entrez). This function
finds all replicates, and then selects the one with the largest value
of the test statistic.
Usage
findLargest(gN, testStat, data = "hgu133plus2")
Arguments
gN
A vector of probe identifiers for the chip.
testStat
A vector of test statistics, of the same length as
gN with the per probe test statistics.
data
The character string identifying the chip.
Value
A named vector of probe IDs. The names are Entrez Gene IDs.
Details
All the probe identifiers, gN, are mapped to Entrez Gene IDs
and the duplicates determined. For any set of probes that map to the
same Gene ID, the one with the largest test statistic is found. The
return vector is the named vector of selected probe identifiers. The
names are the Entrez Gene IDs.
This could be extended in different ways, such as allowing the user to
use a different selection criterion. Also, matching on different
identifiers seems like another alternative.