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genetics (version 1.3.8.1.3)

Depreciated: Depreciated functions

Description

These functions are depreciated.

Usage

power.casectrl(...)

Arguments

All arguments are ignored

Details

The power.casectl function contained serious errors. For some time, replacements were provided by the BioConductor GeneticsDesign package.

In specific, the power.casectl function used an expected contingency table to create the test statistic that was erroneously based on the underlying null, rather than on the marginal totals of the observed table. In addition, the modeling of dominant and recessive modes of inheritance had assumed a "perfect" genotype with no disease, whereas in reality a dominant or recessive mode of inheritance simply means that two of the genotypes will have an identical odds ratio compared to the 3rd genotype (the other homozygote).